Xymogen’s Appe-Curb™

Combatting Cravings Naturally*

Description:

  •  Appe-Curb contains key amino acids to support the biosynthesis of neurotransmitters involved in appetite control, carbohydrate or fat cravings, and mood. Chromium is present to support healthy glucose metabolism and support food intake regulation.* [9,10]
  •  Appe-Curb contains 5-HTP which has been shown to reduce appetite and food intake in healthy obese individuals. [1,2,3]
  •  Appe-Curb contains DL-Phenylalanine which has been found to elevate mood, curb appetite and reduce pain.*
  •  Appe-Curb contains Chromium, as chromium picolinate is widely used to optimize insulin function; thereby preventing swings in blood glucose levels that may be responsible for carbohydrate cravings. [9,10]

Clinical Applications

» Nutritional Support for Carbohydrate, Alcohol & Drug Cravings*
» Supports Healthy Weight (by reducing carbohydrate cravings)*
» Improve Sense of Wellbeing and Energy*
» Supports Healthy Serotonin Levels*
Appe-Curb™ contains key amino acids to support the biosynthesis
of neurotransmitters involved in appetite control, carbohydrate or fat
cravings, and mood. Chromium is present to support healthy glucose
metabolism and support food intake regulation.*

Discussion

 

    • 5-Hydroxytryptophan (“5-HTP”) is a naturally-occurring amino acid
      precursor to serotonin. Numerous studies during the ‘90s, including
      those randomized, double-blind, and placebo-controlled, confirmed
      the safety and efficacy of 5-HTP in reducing appetite and food intake
      in obese healthy and non-insulin-dependent diabetic individuals.[1,2,3] A 2006 study in mice concluded, “5-HTP-induced anorexia may be
      mediated by facilitation of leptin secretion.”[4] Vitamins B6 and C are
      important cofactors in the 5-HTP to serotonin pathway. Among the
      several serotonin receptors thus identified, the 5HT2C receptors are
      suspected in control of food intake. Mice without this receptor exhibit
      increased food intake and become obese.*[5] DL-Phenylalanine (DLPA) is a combination of the d- and the l- forms
      of this essential amino acid. Phenylalanine suppresses appetite by
      regulating the release of cholecystokinin, which in turns signals
      satiety in the brain. D-phenylalanine increases endorphins, while
      L-phenylalanine is an amphetamine-like stimulatory compound. DLPA
      has been found to elevate mood, curb appetite and reduce pain.*
      L-Tyrosine, an essential amino acid is needed for conversion into
      the catecholamine neurotransmitters stress depletes: dopamine,
      norepinephrine, and epinephrine. It is also a precursor for thyroxine.
      Doctors use tyrosine as a mood elevator, to increase alertness after
      sleep deprivation and as an appetite suppressant; although support for
      the latter appears anecdotal.*[6] L-Glutamine, well–recognized for gut and immune support, has also
      been espoused to reduce carbohydrate cravings and support alcohol
      withdrawal, although the mechanism of action for these benefits is not
      known.*[7,8] Chromium, as chromium picolinate is widely used to optimize insulin
      function; thereby preventing swings in blood glucose levels that may
      be responsible for carbohydrate cravings. The mineral in the form
      present was indeed demonstrated to reduce carbohydrate cravings in
      a double-blind, placebo-controlled study.*[9,10]
    • All XYMOGEN® Formulas Meet or Exceed cGMP Quality Standards.
      *These statements have not been evaluated by the Food and Drug Administration.
      This product is not intended to diagnose, treat, cure, or prevent any disease. Rev. 01/08/17

    Appe-Curb™ Supplement Facts

    Serving Size: 4 Capsules
    Servings Per Container: 30

    AMOUNT PER SERVING % DAILY VALUE

    Vitamin C (ascorbic acid)

    500 mg 556%

    Vitamin B6 (as pyridoxine HCl)

    37.5 mg 2206%

    Chromium (as TRAACS® chromium nicotinate glycinate chelate)

    60 mcg 171%

    DL-Phenylalanine

    1 g **

    L-Tyrosine

    750 mg **

    L-Glutamine

    375 mg **

    5-HTP (5-hydroxytryptophan)(from Griffonia simplicifolia)(seed)

    75 mg **

     

    • DIRECTIONS: Take four capsules before breakfast and four capsules before 3 PM,
      or use as directed by your healthcare practitioner. Do not take after 3 PM.
      Consult your healthcare practitioner prior to use if you have, or suspect you have,
      a medical condition or are taking prescription drugs for depression, migraines,
      Parkinson’s disease, or psychiatric disorders. Not for use by children. Do not use
      if tamper seal is damaged.
      CAUTIONS: Do not take if you are, or suspect you are, pregnant or if you are
      lactating.
      STORAGE: Keep closed in a cool, dry place out of reach of children.
      DOES NOT CONTAIN: Wheat, gluten, yeast, soy, animal or dairy products, fish,
      shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified
      organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

    Review of Appe-Curb

    If you have that afternoon slump or craving for sweets, Appe-Curb may help you alleviate those feelings. Appe-Curb contains only natural ingredients to help curb your appetite and does not contain stimulants. It provides a subtle feeling, of fullness and reduces the amount of food you want. [1,2,3]

    Appe-Curb contains the ingredient 5HTP, which has been been shown to reduce appetite and may counteract hunger-inducing hormones which then suppresses appetite. 5 HTP has also been shown to have other benefits such as boosting mood and improving sleep.

    How to Order Discounted Xymogen Products like Appe-Curb

    Click on the following link. Set up your Xymogen account on Wholescripts. Use referral code “Lifespark” and name “Horvath” to set up your account for the lifesparknutrition.com discount. Save your login info and order whenever you want.  https://www.wholescripts.com/register/lifespark.

    If you need help figuring out which supplements are best for your body, please go to SHOP and click on “Medical Grade Supplement Program with Consult.”

    © XYMOGEN

  • DRS-162

7 2 2 5 3 7 5 0 8 9 4 0
References

1. Cangiano C, et al. Eating behavior and adherence to dietary prescriptions in
obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr 1992
Nov;56(5):863-7
2. Cangiano C Effects of oral 5-hydroxy-tryptophan on energy intake and
macronutrient selection in non-insulin dependent diabetic patients. Int J Obes
Relat Metab Disord 1998 Jul;22(7):648-544
3. Amamoto T, Sarai K. On the tryptophan-serotonin metabolism in manicdepressive disorders. Changes in plasma 5-HT and 5-HIAA levels and urinary
5-HIAA excretion following oral loading of L-5HTP in patients with depression.
Hiroshima J Med Sci. 1976 Sep;25(2-3):135-40 [PMID: 1088369] 4. Yamada J, Sugimoto Y, Ujikawa M. Involvement of leptin in hypophagia induced
by the serotonin precursor 5-hydroxytryptophan (5-HTP) in mice. Biol Pharm
Bull. 2006 Mar;29(3):557-9 [PMID: 16508167] 5. Rogers PJ, Blundell JE. Reanalysis of the effects of phenylalanine, alanine,
and aspartame on food intake in human subjects. Physiol Behav. 1994
Aug;56(2):247-50 [PMID: 7938234] 6. http://web.indstate.edu/thcme/mwking/aminoacidderivatives.html {accessed
09 July 07}
7. Goodwin, F. APA Psychiatric News, Dec 5, 1986 in Atkins, R. Dr. Atkins VitaNutient Solution. Simon & Schuster, NY 1998 p169
8. Rogers,L., Pelton, R. Quarterly Journal of Studies of Alcohol, 1957;18(4):581-87
in Atkins, R. Dr. Atkins Vita-Nutient Solution. Simon & Schuster, NY 1998 p169
9. Broadhurst CL, Domenico P. Clinical studies on chromium picolinate
supplementation in diabetes mellitus–a review. Diabetes Technol Ther. 2006
Dec;8(6):677-87 [PMID: 17109600] 10. Docherty JP, et al. A double-blind, placebo-controlled, exploratory trial of
chromium picolinate in atypical depression: effect on carbohydrate craving. J
Psychiatr Pract. 2005 Sep;11(5):302-14 [PMID: 16184071] Additional references available upon request
TRAACS and the Albion Medallion design are registered
trademarks of Albion Laboratories, Inc.

** Daily Value not established.
Other Ingredients: HPMC (capsule), stearic acid, magnesium stearate, medium-chain triglyceride oil, and
silica.

 

 

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