Health, Reviews, Supplements
MEGASporeBiotic™ by Microbiome Labs Review
What is MEGASporeBiotic™?
MEGASporeBiotic™ is a 100% spore-based, broad-spectrum probiotic CLINICALLY shown to maintain healthy gut barrier function. This is a great Probiotic for all types of gut issues and health.
According to Microbiome Labs, this unique all-spore probiotic formula effectively RECONDITIONS the gut by promoting microbial diversity and maintaining key health-promoting, commensal gut bacteria. MegaSporeBiotic™ boasts a 5-year shelf-life, does not require refrigeration, and maintains efficacy during antibiotic therapy.
Why MEGASPOREBIOTIC™ Works for Leaky Gut/Digestive Issues
Megasporebiotic is the first 100% spore-based, broad-spectrum probiotic clinically shown to improve leaky gut in just 30 days.
Spore-based probiotics are much more effective than conventional probiotics on the market because they are designed to survive through the harsh gastric system, colonize, and increase microbial diversity in the gut. Because these spores are so multi-functional, they can support a variety of functions in the body.
This unique all-spore formula effectively reconditions the gut by increasing microbial diversity and encouraging the growth of key health-promoting, commensal gut bacteria. MegaSporeBiotic™ boasts a 5-year shelf-life, does not require refrigeration, and maintains efficacy during antibiotic therapy.**
MEGASPOREBIOTIC™ survives Digestion and Aids Gut Restoration
Megasporebiotic is a great PROBIOTIC because Bacillus spores are naturally designed to survive digestion.
The reason for their inherent survivability comes from their bi-phasic life cycle. This means that the Bacillus spores can transition interchangeably from their dormant form to their active form, depending on the environment. In its dormant spore form, Bacillus will surround itself with an endospore, which is a tough, natural outer shell that protects it from light, heat, pressure, acid, lack of oxygen, and other environmental
factors. This key feature is what allows MegaSporeBiotic™ to survive easily through digestion without the need for enteric-coated capsules or refrigeration.
Once it reaches the intestines, MegaSporeBiotic™ can increase microbial diversity by changing the pH, crowding out unwanted pathogens, and increasing the production of short-chain fatty acids. Due to its inherent survivability and lasting health benefits, MegaSporeBiotic™ has become a revolutionary tool in Total Gut
Restoration.
MEGASPOREBIOTIC™
Probiotic and Antioxidant Combination** Supplement Facts
- 4 Billion CFU
- Bacillus indicus, HU36™
- Bacillus subtilis, HU58™
- Bacillus coagulans (SC-208)
- Bacillus licheniformis (SL-307)
- Bacillus clausii (SC-109)
- 340 mg
OTHER INGREDIENTS: Cellulose, vegetable capsule (cellulose and water).
- Serving Size: 2 Capsules
- Servings Per Container: 30
- Amount Per Serving % Daily Value
- Proprietary Probiotic Blend
- Daily values not established.
- Click here to order discounted Megasporebotic through Fullscript..
- Set up your new Fullscript account with your email and create a password.
- Go to the catalog and find the products you are looking for, including Megasporebiotic.
- You will automatically get a discount by signing up through Lifespark Nutrition.
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Dosing
Children under 5 years of age, please consult with your healthcare practitioner.
Adults and children over 5 years of age: Start with 1/2 or 1 full capsule with a meal and slowly increase using the following protocol:
- Week 1: Take 1 capsule every other day
- Week 2: Take 1 capsule daily
- Week 3+: Take 2 capsules daily
MEGASPOREBIOTIC™ Review
MEGASPOREBIOTIC™ is a great choice for anyone looking to keep a healthy gut.
If you have IBS, constipation, or are constantly getting sick, then you may need to invest in a broad spectrum probiotic like MEGASPOREBIOTIC™.
Products and Ingredients:
- Delivers 4 Billion Cells Daily for Maximum Potency & Absorption
- Supports Healthy Intestines
- Survives the Harsh Digestive Environment
- Supports a Healthy Immune System
- Produces Highly Absorbable ?Carotenoid Antioxidants
- Immune stimulation of peripheral T-lymphocytes and B-lymphocytes to fight colds, flus and infections.
- Decrease in frequency of urinary tract infections.
- Reduction in side effects related to antibiotic therapy.
- Effective treatment for small intestinal bacterial overgrowth (SIBO).
- Diminished duration of diarrhea in children 3 to 36 months of age
- Reduced incidence of irritable bowel syndrome diarrhea.
- Immune response to adenovirus and influenza-A in-vitro.
- Improvement in pain scale in Rheumatoid arthritis patients .
- Reduces the inflammation associated with Crohn’s disease, IBS, ulcerative colitis.
- Improved growth of the natural flora.
- Improved digestion of food and a thus improved?nutrient absorption.
- Production and absorption of critical nutrients –?i.e. carotenoids, quinols, vitamins and enzymes.
- Reduced risk of cardiovascular disease.
- Reduction of cholesterol.
- Detoxification of the intestinal tract.
- Effective colonization.
Triglyceride and Probiotics Study Published
Microbiome Labs announced that their recent study, Efficacy of Spore-Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial, has just been published in Integrative Medicine: A Clinician’s Journal.
Approximately 1/3 of the population has elevated triglyceride levels (> 150 mg/dL) in the bloodstream, or hypertriglyceridemia (HT). In addition to cholesterol levels like LDL and HDL, elevated levels of triglycerides are also commonly used as indicators for heart disease risk.
Due to the metabolic functions of the gut microbiome, an imbalance of gut bacteria (gut dysbiosis) can increase serum triglycerides by increasing intestinal permeability and allowing for bacterial endotoxin translocation into circulation.
Finally, excessive intake of certain dietary fat stimulates triglyceride production in the liver. As triglycerides circulate the body, they can contribute to plaque formation in arteries, fatty build-up around the liver, and systemic inflammation.
Reference
Campbell AW, Sinatra D, Zhang Z, et al. Efficacy of Spore Forming Bacilli Supplementation in Patients with Mild to Moderate Elevation of Triglycerides: A 12 week, Randomized, Double-Blind, Placebo Controlled Trial. Integrative Medicine. 2020;19(2):18-23.
Customer Service:
Online Reviews/Complaints:
- Click here to order discounted Megasporebotic through Fullscript..
- Set up your new Fullscript account with your email and create a password.
- Go to the catalog and find the products you are looking for, including Megasporebiotic.
- You will automatically get a discount by signing up through Lifespark Nutrition.
- Save your log in and you may order any time through Fullscripts whenever you need too!
Sources:
- MCFARLIN BK, HENNING AL, CARBAJAL KM. Oral spore-based probiotic supplementation was associated with a reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers. World J Gastrointest Pathophysiol. 2017 Aug 15; 8(3): 117–126.
- RHEE KJ, SETHUPATHI P, DRIKS A, ET AL. Role of commensal bacteria in the development of gut-associated lymphoid tissue and preimmune antibody repertoire. J Immunol. 2004;172(2):1118-24.
- DE PUNDER K, PRUIMBOOM L. Stress induces endotoxemia and low-grade inflammation by increasing barrier permeability. Front Immunol. 2015;15(6):223
- GONG Y, LI H, LI Y. Effects of Bacillus subtilis on epithelial tight junctions of mice with inflammatory bowel disease. J Interferon Cytokine Res. 2016;36(2)
- SAMANYA M, YAMAUCHI K. Histological alterations of intestinal villi in chickens fed dried Bacillus subtilis var. natto. Comp Biochem Physiol A Mol Integr Physiol. 2002;133(1):95-104
- TAM NKM, UYEN NQ, HONG HA, ET AL. The Intestinal Life Cycle of Bacillus subtilis and Close Relatives. Journal of Bacteriology. 2006;188(7):2692-2700.
- “SURVIVAL OF PROBIOTICS IN SIMULATED GASTRIC FLUID.” Food Science Center Report. Silliker Labs. RPN 16663. August 24, 2013.
- GIBSON GR, ROUZAUD G, BROSTOFF J, ET AL. An evaluation of probiotic effects in the human gut: microbial aspects. Final Technical report. FSA project ref G01022.
- LEFEVRE M, RACEDO SM, RIPERT G, ET AL. Probiotic strain Bacillus subtilis CU1 stimulates immune system of elderly during common infectious disrandomized, double-blind placebo-controlled study. Immun Aging. 2015;12:24.
- SERRA CR, EARL AM, BARBOSA TM, ET AL. Sporulation during Growth in a Gut Isolate of Bacillus subtilis. J Bacteriol. 2014;196(23):4184-4196.
- HONG HA, KHANEJA R, TAM NMK, ET AL. Bacillus subtilis isolated from the human gastrointestinal tract. Res Microbiol. 2009;160(2):134-143.
- MANDEL DR, EICHAS K, HOLMES J. Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial. BMC Complement Altern Med. 2010;10:1.
- MARSEGLIA GL, TOSCA M, CIRILLO I, ET AL.ease period: a Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study. Ther Clin Risk Manag. 2007;3(1):13-7.
- URDACI MC, BRESSOLLIER P, PINCHUK I, ET AL. Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities. J Clin Gastroenterol. 2004;38(6 Suppl):S86-90.
- NISTA EC, CANDELLI M, CREMONINI F, ET AL. Bacillus clausii therapy to reduce side-effects of anti-Helicobacter pylori treatment: randomized, double-blind, placebo controlled trial. Aliment Pharmacol Ther. 2004 Nov;20(10):1181-8.
- GABRIELLI M, LAURITANO EC, SCARPELLINI E, ET AL. Bacillus clausii as a Treatment of Small Intestinal Bacterial Overgrowth. Am J Gastroenterol. 2009;104(5):1327-8.
- DI CARO S, TAO H, GRILLO A, ET AL. Bacillus clausii effect on gene expression pattern in small bowel mucosa using DNA microarray analysis. Eur J Gastroenterol Hepatol. 2005;17(9):951-60.
- CIPRANDI G, TOSCA MA, MILANESE M, ET AL. Cytokines evaluation in nasal lavage of allergic children after Bacillus clausii administration: A pilot study. Pediatr Allergy Immunol. 2004;15(2):148-51.
- CASULA G, CUTTING SM. Bacillus Probiotics: Spore Germination in the Gastrointestinal Tract. App Environ Microb. 2002;68(5):2344-2352.
